产品货号:
Z31894
中文名称:
CD3E抗体
英文名称:
Anti-CD3E Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CD3E Antibody |
指标别名 | CD3;CD3 epsilon;CD3E;CD3-epsilon;T3E;TCRE |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | IHC,ICC/IF,IP |
基因名称 | CD3E |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human CD3 epsilon |
成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | The CD3 complex mediates signal transduction.When T cells encounter antigens via the T cell receptor (TCR),information about the quantity and quality of antigens is relayed to the intracellular signal transduction machinery.This activation process depends mainly on CD3 (Cluster of Differentiation 3),a multiunit protein complex that directly associates with the TCR.CD3 is composed of four polypeptides:ζ,γ,ε and δ.Each of these polypeptides contains at least one immunoreceptor tyrosine-based activation motif (ITAM).Engagement of TCR complex with foreign antigens induces tyrosine phosphorylation in the ITAM motifs and phosphorylated ITAMs function as docking sites for signaling molecules such as ZAP-70 and p85 subunit of PI-3 kinase.TCR ligation also induces a conformational change in CD3ε,such that a proline-region is exposed and then associates with the adapter protein Nck. |
Uniprot ID | P07766 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | T-cell surface glycoprotein CD3 epsilon chain |
推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:50~200 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~200 Immunocoprecipitation (IP) 1:50 |
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