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所在位置:所有产品 > 抗体抗原 > 一抗 > CD3E抗体
CD3E抗体图片
产品货号:
Z31894
中文名称:
CD3E抗体
英文名称:
Anti-CD3E Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-CD3E Antibody
指标别名CD3;CD3 epsilon;CD3E;CD3-epsilon;T3E;TCRE
克隆性Monoclonal
检验物种human
应用范围IHC,ICC/IF,IP
基因名称CD3E
抗体来源Rabbit
抗体类型IgG
免疫原A synthesized peptide derived from human CD3 epsilon
成分Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料The CD3 complex mediates signal transduction.When T cells encounter antigens via the T cell receptor (TCR),information about the quantity and quality of antigens is relayed to the intracellular signal transduction machinery.This activation process depends mainly on CD3 (Cluster of Differentiation 3),a multiunit protein complex that directly associates with the TCR.CD3 is composed of four polypeptides:ζ,γ,ε and δ.Each of these polypeptides contains at least one immunoreceptor tyrosine-based activation motif (ITAM).Engagement of TCR complex with foreign antigens induces tyrosine phosphorylation in the ITAM motifs and phosphorylated ITAMs function as docking sites for signaling molecules such as ZAP-70 and p85 subunit of PI-3 kinase.TCR ligation also induces a conformational change in CD3ε,such that a proline-region is exposed and then associates with the adapter protein Nck.
Uniprot ID P07766
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称T-cell surface glycoprotein CD3 epsilon chain
推荐稀释比
Immunohistochemistry in paraffin section (IHC) 1:50~200
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~200
Immunocoprecipitation (IP) 1:50

相关搜索:CD3E抗体CD3E单抗Anti-CD3E Antibody
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